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The combination of the release profile and the dosage regimen (IM injections every 2 weeks) of RISPERDAL® CONSTA® results in sustained. Let your healthcare professional know if these symptoms occur RISPERDAL CONSTA ® (risperidone) long-acting injection is indicated as monotherapy or as adjunctive therapy to lithium or valproate for the maintenance treatment of Bipolar I Disorder and for the treatment of schizophrenia. Approved for use in people with Schizophrenia and related psychoses, and for acute mania associated with Bipolar disorder. If you already use other antipsychotic medication, you may need to keep using it for a short time Risperdal Consta® (risperidone long-acting injection) should be administered every two weeks by deep intramuscular deltoid or gluteal injection using the appropriate safety needle. You may also need to take risperidone by mouth in pill or liquid form during the first 3 weeks of your treatment with the injections. PERSERIS kit should be brought to room temperature for at least 15 minutes before mixing 1 2. , dehydration, hypovolemia, treatment with antihypertensive medications). Inject medication Insert needle fully into the subcutaneous tissue. Administration: For intramuscular injection only. Painful, long lasting erections have been reported with. Subcutaneous abdominal administration that must be performed by an HCP. 1 Step 4 Peel the safety needle pouch halfway open. NOTE: Recommended injection angle is 45 degrees, but the actual angle of injection will depend on the amount of subcutaneous tissue. Given during the first 3 weeks of treatment with RISPERDAL® CONSTA® to maintain therapeutic levels until the main release of risperidone from the injection site has begun (see DOSAGE AND ADMINISTRATION). PERSERIS is for subcutaneous administration only. Follow your doctor's dosing instructions very carefully. Long-acting injectable risperidone (RLAI) has recently been approved for maintenance treatment in patients with bipolar I disorder. IMPORTANT SAFETY INFORMATION FOR RISPERDAL CONSTA®(risperidone). 8)] Risperdal Consta ® should be administered every 2 weeks by deep intramuscular (IM) deltoid or gluteal injection. 8)] Both hyperthermia and hypothermia have been reported in association pepcid instructions use with RISPERDAL CONSTA ® use. Quiroz JA, Yatham LN, Palumbo JM, Karcher K, Kushner S, Kusumakar V. Risperdal Consta® is usually given every 2 weeks RISPERDAL CONSTA®(risperidone) long-acting injection is indicated as monotherapy or as adjunctive therapy to lithium or valproate for the maintenance treatment of Bipolar I Disorder and for the treatment of schizophrenia. RISPERDAL CONSTA® may increase difficulty in swallowing that may cause food or liquid to get into your lungs. Reconstitution PERSERIS requires thorough mixing of 60 cycles to uniformly combine the risperidone powder and delivery system liquid 1 3. Risperidone is injected under the skin or into a muscle. Do not inject by any other route. The information for your doctor or nurse on the right way to reconstitute. Thrombotic Thrombocytopenic Purpura (TTP) has been reported. 1 Step 3 While holding the syringe upright, remove the rubber tip cap with an easy clockwise twisting motion. Risperdal Consta is usually given once every 2 weeks RISPERDAL CONSTA should be administered every two weeks by deep intramuscular deltoid or gluteal injection using the appropriate safety needle. Inject the medication slow and steady. Drug information provided by: IBM Micromedex. IMPORTANT SAFETY INFORMATION FOR RISPERDAL CONSTA® (risperidone). Follow your doctor's instructions. Eligible patients pay per dose with a ,500. Titusville, NJ: Janssen Pharmaceuticals, Inc. Shake the syringe vigorously for at least 10 seconds to ensure a homogeneous suspension. (2) • Upward dose adjustment of RISPERDAL ® CONSTA ® should not be made more frequently. 1 Step 2 Select the appropriate needle. Evidence supporting the use of RLAI for this indication consists of several nonrandomized, open-label studies; one randomized, open-label trial; and two adequately powered randomized, double-blind trials Janssen CarePath Savings Program for RISPERDAL CONSTA®. For deltoid administration, use the 1-inch needle alternating injections between the two arms. Care should be taken to avoid inadvertent injection into a blood vessel You may need to take risperidone by mouth (in pill or liquid form) before you start receiving risperidone injections. The medication effects last for approximately 2 weeks RISPERDAL CONSTA ® should be administered every 2 weeks by deep intramuscular (IM) deltoid or gluteal injection. 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