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If the last dose of Invega Hafyera was 1,092. Risperdal Consta is injected into a muscle. Follow your doctor's instructions RISPERDAL CONSTA ® should be administered every 2 weeks by deep intramuscular (IM) deltoid or gluteal injection. J&J said in a filing with the U. Oral supplementation should be continued for 3 weeks after the first injection until the main release of risperidone from the injection site has begun How is Risperdal Consta given? For gluteal administration, use the 2-inch needle alternating injections between the two buttocks therapeutic plasma concentrations from RISPERDAL® CONSTA®. Risperdal Consta is usually given once every 2 weeks. Administration: For intramuscular injection only. You may also need to take risperidone by mouth in pill or liquid form during the first 3 weeks of your treatment with the injections. Care should be taken to avoid inadvertent injection into a blood vessel If a total daily dose of at least 2 mg oral RISPERDAL ® is well tolerated, an injection of 25 mg Risperdal Consta ® can be administered every 2 weeks. The clearance of risperidone and risperidone plus 9-hydroxyrisperidone was 13. (2) • Avoid inadvertent administration into a blood vessel. Securities and Exchange Commission on Friday that it reached a settlement in principle in September to resolve "substantially all" of the roughly 9,000 cases that the New Brunswick, New Jersey-based drugmaker faced over Risperdal.. Thrombotic Thrombocytopenic Purpura (TTP) has been reported. 5 mg / 2 ml Belgium Janssen Cilag N. The administration process consists of several steps that are performed to reconstitute the drug, assemble the syringe, administer the drug, and safely dispose of the kit (Fig. Both hyperthermia and hypothermia have been reported in association with RISPERDAL CONSTA ® use. For deltoid administration, use the 1-inch needle alternating injections between the two arms RISPERDAL® CONSTA® administration is 3 to 6 days, and is associated with a monoexponential decline in plasma concentrations. This half-life of 3-6 days is related to the erosion of the microspheres and subsequent absorption of risperidone. 5 mg Powder and solvent for solution for injection Intramuscular use 37. We developed this step-by-step injection kit animation for Janssen to walk patients and nurses through the entire process The Risperdal ® CONSTA ® kit consists of components that are assembled and reconstituted prior to intramuscular injection. A healthcare provider will give you this injection. The recommended starting dose is 25 mg Risperdal Consta every two weeks. (2) • Upward dose adjustment of RISPERDAL ® CONSTA ® should not be made more frequently than every 4 weeks. Patients can be given up to 2 weeks before or 3 weeks after the scheduled 6-month dose. For deltoid administration, use the 1-inch needle alternating injections between the two arms. Follow your doctor's instructions RISPERDAL CONSTA should be administered every two weeks by deep intramuscular deltoid or gluteal injection using the appropriate safety needle. Timing of Missed Maintenance Dose. Care should be taken to avoid inadvertent injection into a blood vessel Risperdal Consta is injected into a muscle. Patients on higher dosages of the used oral antipsychotic should be considered for the higher Risperdal Consta dose of 37. Clinical effects of each upward dose adjustment should not be anticipated earlier than 3 weeks after injection. Refrigerated storage PERSERIS should be refrigerated for storage. Missed dose more than 6 months and 3 weeks, up to but Less than 8 months since last dose, do not administer the next dose of Invega Hafyera, instead use a re-initiation regimen. It can remain at room temperature in its original carton (68°F to 77°F) for up to 7 days prior to administration 1 Discard after 7 days at room temperature 1 PERSERIS kit should be brought to room temperature for at least 15 minutes before mixing 1 2. Each injection should be administered by a health care professional using the appropriate enclosed safety needle [see Instructions For Use ]. Roderveldlaan 1, 2600 Berchem, Belgium Risperdal Consta 50 mg Powder and solvent for solution for injection Intramuscular use 50 mg / 2 ml Bulgaria Johnson & Johnson D.