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To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and take usage can with and information we have about you.. The advantage of taking a particular brand is that. He said that the generic range is not accurate and is a range of 10% too high or low. Can generic Synthroid cause weight gain? Intolerable for most Levothyroxine is a synthetic prohormone proven to be effective in the management of hypothyroidism. A better one would be Synthroid plus Cytomel. Answer (1 of 10): Take the generic for 3 months and get your labs redone. Most medications are available in brand-name and generic preparations Synthroid is available as a generic drug called levothyroxine. Synthroid is also used in patients who need surgery and radioiodine therapy to manage a type of thyroid cancer called well-differentiated thyroid cancer. All my prescriptions are written for non generic and the doctor adds: do not substitute Answer (1 of 5): This has been a discussion every since the first generic synthroid was released over 40 years ago. After total thyroidectomy ), your thyroid level will fluctuate if you get different brands of thyroid or generics from different companies What my endocrinologist said today. After total thyroidectomy ), your thyroid level will fluctuate if you get different brands of thyroid or generics from different companies. Other pharmaceutical companies can then come in and make a "me too" version of the medication and they often sell it for cheaper than the original Consistency of med: There is no problem with generic thyroid as long as you have some underlying thyroid function. Understanding your test results T4 and TSH results: The T4 test and the TSH test are the two most common thyroid function tests Synthroid has an average rating of 6. 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